Date: 2007-05-14 08:05 am (UTC)
Recent advances in science have shown that the human body may respond to light with much more than just with the cones and rods of the retina. I tracked down a good review (http://www.bmj.com/cgi/content/full/317/7174/1704) which towards the bottom mentions a 1998 paper in Cell, "However, when mammalian cell lines were first deprived of serum and then exposed to a high concentration of serum with all of its rich soup of signalling factors, the cells in culture very quickly turned on a large number of genes, among them mammalian per. ... This landmark study opens up an enormous range of opportunities and questions, not the least of which is whether every cell in our body has the potential to be a circadian clock."

A Science paper in 1997 noted that Per is active all over the fly, not just in the eyes (from a NIMH article (http://www.nimh.nih.gov/publicat/bioclock.cfm)). The Tim protein (http://cal.man.ac.uk/student_projects/1999/sanders/mech.htm) that links to Per and takes it into the nucleus to create more Per is destroyed by light. All wavelengths of light? How about after the light penetrates the skin, what wavelengths exist then?
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